The Finance Ministry goes to Mario Marcel, whose term as Central Bank president was widely praised by financial analysts.
Boric will turn 36 before taking office on March 11 and his cabinet includes at least six ministers under the age of 40, including those who led a wave of protests in 2011 for improved, free education.
His term will coincide with a public referendum on a new constitution that is being drafted by a constituent assembly, potentially changing the shape of the political system as a whole.