The film stars Tom Holland and Zendaya as Peter Parker and MJ as they battle villains from across the Marvel multiverse.
It’s a remarkable milestone in a pandemic, and it signals No Way Home” will likely become the only film of the Covid era to open to a more-than-$100-million opening weekend.
The film — which cost $200 million to make — is opening in more 4,300 theaters.
“Peter Parker is the every-person who anyone can identify with,” Robbins added.
Peter Parker asks Doctor Strange to help him reset reality after Parker’s secret identity is found out.
The Omicron variant could hurt box office returns this weekend and in the weeks to come, and a portion of the potential audience may decide to wait for the film’s eventual release at home, Dergarabedian said.